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History of Enderlein

Excerpted from "Bacteria Cyclogeny" by Professor Dr. Günther Enderlein.
Now available for purchase online!

Günther Enderlein (1872 - 1968) was born into a family of teachers in Leipzig. After earning his high school diploma, he studied in the natural sciences at the university, specializing in zoology. He was graduated summa cum laude.

He became curator of the Berlin Zoological Museum. He wrote over 500 scientific papers as a zoologist. Enderlein founded his own microbiological institute in Berlin, where he developed new types of preparations from molds. He later became production manager at the Sanum firm (Berlin/Hamburg). After the facilities were moved to Aumühle in the vicinity of Hamburg, he devoted himself totally to setting up his own enterprise, "Ibica".

Enderlein died in 1968, and the firm was able to continue on only a few years under the leadership of his widow, Sigrid Enderlein. When the production facilities were taken over by Sanum-Kehlbeck in Hoya, the preparations program was improved and expanded based on the latest scientific findings. The most important areas of activity at the Ibica Institute had to do with Pleomorphism and symbiosis, building on the research of Antoine Bechamp. The fate of this researcher closely resembles that of Enderlein: he too had to struggle against prejudice and error.

In his best-known work, on the "microzymes", Bechamp declared that all animal and plant cells contained minuscule granules (Granulations moléculaires) that did not die when the organism died, but rather lived on. He said they were the source of fermentation, and that microorganisms could arise from them as well (cited from Dunbar).

This brief statement formed the basis for Pleomorphism - the direction in which future research should have moved. However, Pasteur's influence was able to establish the view that microbes could be classified into fixed and unchangeable species and genera. Each species was said to cause a specific disease.

Bechamp's findings were sacrificed to Pasteur's error. Bechamp was the first scientist to describe at least the beginnings of bacterial Cyclogeny (kyklos = circle, cycle; genos = birth, origin). Not blinded by authority, nor corrupted by greed for profits, and immune to falsification of reality, he was able to interpret natural phenomena correctly - to which may well be added what Enderlein called a "dash of intuition". This would correspond roughly to the concept of "premonition".

Contemporary science is little blessed with this auxiliary "sense organ". "Premonition" presupposes feelings and emotions that are missing or could be present in many areas. Many are barred forever from the understanding of certain kinds of elementary knowledge. Woe unto us, should science ever come to be dominated by one-dimensional logic-choppers! The consequences would be cover-ups and persecution of anything that fell outside of conventional understanding.

(Galileo: "I believe that there is no greater hate in the world than that of ignorance toward knowledge.") In 1916, Enderlein discovered something upon which many changes in this world depend. While doing work on typhus, he observed, under a darkfield microscope, minuscule mobile living organisms in the blood, that merged with higher-level bacteria. The products of this copulation disappeared from view in a flash. Enderlein suspected he was observing sexual processes here, in which lower - rather than higher (as in embryonal development) - forms arose, invisible to the eye in a light microscope. These flagellated, highly mobile elements were named "Spermit".

Enderlein had also discovered that the blood of all mammals contained a symbiont of plant origin. This organism turned up in various forms, which, among other things, performed vital functions related to blood clotting (thrombocytes). All of life turned out to be a "gigantic symbiosis", for vertebrates could not have arisen if blood had not been able to clot. Healthy life had to be a eusymbiosis; this meant that disease had to represent a disturbed symbiosis. To be sure, the discovery of the "Spermit" did not solve the Riddle of the Ages, but at least the secret of life up to the limits of knowledge was elucidated. Having once penetrated to the basis of life, the microbial life-cycle could quickly be described in all its variety of form. This description is contained in Bacteria Cyclogeny. Here is shown that no unit of life thinks, in the "struggle to survive", in terms of eliminating other life-forms. On the contrary, one can see each species striving for equilibrium with the other species in its environment. Eating and killing is kept down to the amount necessary for the survival of the species. Anyone needing proof will find it in the darkfield by observing Spermit activity in the blood. As soon as reproduction and upward development of the botanical symbiotic partner known as the "Endobiont" is forced by some influence or another, supernumerary symbiont elements are removed from circulation by copulation processes. In all this, there are many possibilities and side-effects (pseudo-crystal formation) that cannot be gone into here. These adaptive necessities are called diseases, but they are healing processes, attempts to shunt a disturbed symbiosis back to the original healthy track.

It is impossible - nor is it the task of this introduction - to fully acknowledge Enderlein's life-work in its comprehensive entirety. For this, one must turn to his bibliography.

Reference can only be made here to a very abbreviated summary of his basic findings:

  • The proof that bacteria possess a nucleus or nuclear equivalent (Mych)
    This knowledge was vehemently disputed by the expert opinion of the time, yet confirmed a scant 20 years later by the development of the phase-contrast and electron microscopes (Knöll and Zapf, Kölbel and many others).

  • The proof of the sexual reproduction of bacteria
    For all microbes, Enderlein distinguishes between sexual and asexual reproduction - and, further, between the formation of larger microbial forms (the valence intensification of Probaenogeny) and the purely numerical reproduction of Auxanogeny. Asexual reproduction takes place via budding and division, while the sexual form involves copulation and nuclear fusion. Forty years later, sexual reproduction was confirmed by subsequent research (Nobel Prize winners J. Lederberg and E. Taumg (USA), and W. Hayes (Edinburgh) without a single mention of Enderlein's priority.

  • The establishment of the Pleomorphism of microbes
    This theory states that, under certain precisely-defined conditions, a particular microbial species can manifest itself in various forms and developmental stages, from the minutest levels at ultramicroscopic size scales up to the large, polynuclear, highly-developed stages of e.g. bacteria and fungi.

Recent microphotographs have confirmed the metamorphosis of bacterial forms - anticipated and thoroughly described by Enderlein - from single-rod into doubled, quadrupled and octupled forms, as well as the presence of branching and non-acid-resistant stages in Mycobacterium tuberculosis. Above all, H. Kölbel of the Tuberculosis Research Institute in Borstel has recently provided much supporting evidence. No less a personage than the Nobel Prize winner G. Domagk has explicitly pointed out the significance of the presence of non-acid-resistant stages in Mycobacterium tuberculosis. The Japanese tuberculosis researcher Saburo Uyeda was worked out further details of the interrelationships between these growth forms in tissue. H. Harmsen has reported in summary forms about these and other research results, specifically remarking that many of Günther Enderlein's earlier demonstrations have now been largely confirmed. However, many reports have failed to mention this.

In his Bacteria Cyclogeny, Enderlein so comprehensively describes the developmental cycle for cocci, bacilli, spirilla and plasmodia that today no one can anymore ignore the fact of considerable species-specific form changes in bacteria.

The smallest unit, the Protit, is a minuscule living protein particle. It can reproduce one-dimensionally into a tiny filament, the Filum; it can reproduce or associate two- or three-dimensionally into the Symprotit.

The Chondrit stage is characterized by a constant

generational alternation between Filum and Symprotit.

The bacterial flagella are Fila, and thus forms of the Chondrit stage. Depending on the biological conditions, each flagellum can re-develop into the corresponding bacterial species. This also includes the "bacteriophages", which are flagellated Symprotit (Spermit).

Their fusion (copulation) with higher-valence bacterial forms leads to their metamorphosis into the Chondrit stage, and thus to their apparent disappearance, as noted above.

These facts were not yet known on 10 June 1914, when, at a meeting of the Berlin Medical Society von Klemperer, Meyer, Frank presented their accusation against Friedmann that his preparation (Utilin) had been intermixed with bacterial spheres and the like. At the time, Friedmann had no means at hand for repudiating these insinuations. It later became clear that precisely the mycobacterial strain under discussion produces many subsidiary forms in the Pleomorphic sense, i.e. there was no contamination. Enderlein emphasized time and again that there is no way that such a contaminated mixed culture could have been kept viable for half a century.

  • The proof that there is no such thing as sterile, germ-free blood
    The serum of all men (and all other warm-blooded species) normally contains microorganisms that Enderlein calls the Endobiont. The newer scanty designations in this context, such as microsomes, chondriosomes, etc. show no consideration whatever of Enderlein's 40-year priority. Rather, they proceed from the assumption that these are blood elements, i.e. components of one's own body. On the other hand, Enderlein's research has shown that there exists a developmental form of the Endobiont that is vegetal in nature. This assertion of Enderlein's has been confirmed by British researchers, who detected plant enzymes in thrombocytes - again, however, without mentioning Enderlein's research work.

Man lives with the Endobiont, i.e. a plant microorganism, symbiotically. Every single human being acquires this Endobiont diaplacentally and harbors at least its primitive stages in cells and body fluids throughout life. They are even present in human sperm and egg cells, i.e. from impregnation on, in the earliest developmental stages of the new being, according to Leschke. It is thus nothing new for Gerlach to declare that the fetus in the mother's body already contains what he termed "myoplasma". In the Endobiontic developmental series, the lower stages, Protit and Chondrit, are apathogenic.

In the Chondrit stage, they can be used therapeutically as remedies. All the higher valences of the Endobiont can encourage or cause diseases, whereby they appear not only in the blood and blood cells, but also - from certain stages on - also in tissue cells, exerting a degenerative influence on them.

The upward development of the Endobiont is caused or favored, among other things, by the continual harmful influences of our civilization (artificial fertilizers, chlorinated water, polluted air, etc.) but primarily by a false diet that outright "fattens up" the Endobiont with its too-high protein and sugar content.

According to Enderlein, the diseases of the Endobiosis complex are based on the upward development of the Endobiont to higher-valence, parasitic growth forms with a characteristic metabolism that poisons the human body fluids (highly potentiated lactic acid production). This reduces the regulatory equilibrium in the mutual relationship with the vegetative centers in the diencephalon, which brings about the failure of its shape and formative function.

  • Disease means disturbed symbiosis
    The plant symbiont spreads throughout the warm-blooded body, either numerically by means of simple reproduction or through the formation of higher developmental forms, which clog up circulatory organs (prethrombosis, capillary thrombosis).

  • Disturbed symbiosis is detected in the darkfield from the absence of certain growth forms of the Endobiont (Diecothecit)
    As bioregulators, these maintain symbiotic equilibrium. At the same time, various pathogenic cell elements appear.

  • Restoration of symbiotic equilibrium
    (Disease healing) is only possible when the body is once again given what it has lost (the bioregulators, which - by means of nonviolent restructuring processes - dismantle higher parasitic developmental forms and excrete them via the kidneys, skin, etc.).

  • Issues of health exclusively concern life-processes
    They can therefore only be resolved through the science of biology.

From the orthodox side, Enderlein has been accused of refusing to use the generally-accepted nomenclature. How is it possible to use accepted scholarly terminology if one is describing things that don't even exist in the standard doctrine?

For example, many manifestations with the empty designation "organelle" are not at all recognized by standard doctrine as symbiontic cycle stages! Clearly, new terms need to be found for these. Enderlein has - whenever possible - adopted established terms, scrupulously respecting priority rights.

Some examples from hematology:

Well-known fibrin is, according to Enderlein, by no means a precipitate from protein coagulation, but rather the Endobiont's Chondrit dendroid.

Peripheral granules of the erythrocytes are not organelles (Schilling), but rather Symprotit of the Endobiont.

Reticulocytes (Heilmeyer) do not represent erythrocytes with special organelles, but rather erythrocytes internally infested by Endobiont Chondrit trees.

The megaloblasts of pernicious anemia do not represent nucleated erythrocytes, but rather erythrocytes possessing an internal colony of Endobiont Chondrit that bloat them up to an abnormal size (pseudo-nucleus).

Those are - very succinctly formulated - some essential features of Günther Enderlein's work - who was unfortunately unable to experience the present worldwide scientific trend to Pleomorphism in its full extent.

His contemporaries did not always understand him fully. What Johann Wolfgang von Goethe once stressed applies here: "But in the sciences, that which has been passed on and learned at the academies will be regarded as one's personal possession. Now, if someone comes along with something new that contradicts - and threatens to overthrow - the credo we have repeated mechanically for years and in turn passed on to others, then all passions are raised against it, and no effort is spared to suppress it. It is resisted by any and every means: one acts as if one had not heard anything; one speaks of it deprecatingly, as if were not even worth looking at and investigating. And thus a new truth can wait a long time to establish itself.

Or, to cite Alexander von Humboldt, every idiocy takes the Germans 200 years: 100 to commit it, 100 to realize what they've done.

In the struggle to preserve and restore health, this new edition of Bacteria Cyclogeny by Günther Enderlein will definitely help shorten the latter period.

Alfred Baum, MD
Physician and bacteriologist
Hanover, August 1981


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